hrp0082p1-d2-244 | Thyroid (1) | ESPE2014

Treatment of Graves’ Disease with Methimazole in Children Alters the Proliferation of Treg Cells and T Lymphocytes

Klatka Maria , Grywalska Ewelina , Wasiak Magdalena , Rolinski Jacek

Background: GravesÂ’ disease (GD) is almost always the cause of hyperthyroidism in children. Studies carried out for recent years confirm an important role of T regulatory cells (Tregs) in the development of autoimmune diseases. However, the interactions between T-cell response and Treg proliferation in GD is still poorly understood.Objective and hypotheses: The aim of this research was the assessment of the in vitro proliferation of Treg ce...